منابع مشابه
Antithrombogenic modification of small-diameter microfibrous vascular grafts.
OBJECTIVE To develop small-diameter vascular grafts with a microstructure similar to native matrix fibers and with chemically modified microfibers to prevent thrombosis. METHODS AND RESULTS Microfibrous vascular grafts (1-mm internal diameter) were fabricated by electrospinning, and hirudin was conjugated to the poly (L-lactic acid) microfibers through an intermediate linker of poly(ethylene ...
متن کاملDevelopment of a probucol-releasing antithrombogenic drug eluting stent.
The success of drug eluting stents (DESs) has been challenged by the manifestation of late stent thrombosis after DES implantation. The incomplete regeneration of the endothelial layer poststenting triggers adverse signaling processes precipitating in thrombosis. Various approaches have been attempted to prevent thrombosis, including the delivery of biological agents, such as estradiol, that pr...
متن کاملThick Description
I In her book, Philosophy in a New Key, Susanne Langer remarks that certain ideas burst upon the intellectual landscape with a tremendous force. They resolve so many fundamental problems at once that they seem also to promise that they will resolve all fundamental problems, clarify all obscure issues. Everyone snaps them up as the open sesame of some new positive science, the conceptual center-...
متن کاملEffects of antithrombogenic agents on microvenous anastomoses in a rat model.
OBJECTIVE To compare venous thrombosis rates among animals treated with aspirin, clopidogrel bisulfate, and ketorolac tromethamine using an anastomotic "tuck" model. DESIGN Single-blind randomized animal study. SETTING An animal laboratory at a tertiary care academic referral center. SUBJECTS Forty-two retired Lewis breeder rats divided into 3 equal groups. INTERVENTIONS Before surgical...
متن کاملThrough Thick and Thin
Patients with symptoms caused by hypertrophic obstructive cardiomyopathy are treated with β-blockers, verapamil, and disopyramide. Novel drugs are under development. The minority of patients whose symptoms interfere substantially with lifestyle despite optimal pharmacological management may be offered septal reduction therapy with ablation or myectomy. Other mechanical therapies, including shor...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Interventions
سال: 2017
ISSN: 1941-7640,1941-7632
DOI: 10.1161/circinterventions.117.005663